Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS

The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

NARCOMS Patient Registry

Register as a willing MS research participant to facilitate multicenter studies. Initiated by the Consortium of MS Centers.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

Clinical Trial: Comparing Experimental Tolebrutinib with Aubagio® in Relapsing MS

PLEASE NOTE: ENROLLMENT IN THIS STUDY HAS BEEN PLACED ON HOLD IN THE UNITED STATES BY THE FDA DUE TO SOME CASES OF LIVER INJURY. PLEASE SEE HERE FOR MORE INFORMATION. SUMMARY: Investigators are recruiting a total of 1800 people with relapsing forms of MS worldwide for ...

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Clinical Trial: Computerized Cognitive Rehabilitation

This study examines a home-based computerized cognitive rehabilitation intervention focused on improving attention, learning, and memory in adults with MS, compared to a placebo intervention (a videogame). Enrolled participants will complete a series of mental ability eval...

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Clinical Trial: Efficacy of Diet on Quality of Life in MS

Please see below for travel reimbursement information. This is a research study comparing the effects of three diets — a Modified Paleolithic Diet (elimination of gluten, dairy, and eggs), a Time Restricted Olive Oil-based Ketogenic diet, and usual diet with informatio...

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Clinical Trial: Evaluating Mobility Interventions in the Real World

What is this study about? We want to study the best ways to help people walk and run better using lower-limb orthoses (leg braces). To do this, we will study people who use orthoses, as well as people who don’t. What will happen during the study? You might do an...

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Clinical Trial: Exercise Training Effects on Cognition and Brain Function in MS

This research study is examining the effects of exercise training in persons with multiple sclerosis who have been on any stable disease-modifying therapy for at least 6 months. The study is interested in examining the influence of supervised aerobic walking exercise or stretc...

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Clinical Trial: Exploratory Study of Entire-body PET Scans for Multiple Sclerosis

Can an entire-body positron emission tomography (PET) scanner be used to improve evaluation, monitoring and measurement of both peripheral and central damage to nerve-insulating myelin (demyelination) in people with MS? We assume here that demyelination outside the brain may i...

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Clinical Trial: Fenebrutinib

A study to evaluate the effectiveness and safety of fenebrutinib on disability progression and relapse rate. Eligible participants will be randomly assigned to receive either fenebrutinib or teriflunomide. Some may then receive fenebrutinib during an open label extension.

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Clinical Trial: Gait training to improve walking

Over 90% of persons with MS complain of difficulty with walking. High intensity interval gait training, where persons alternate brief periods of walking at high speeds with periods of rest has been found to improve walking in other neurologic diagnoses. However, its impact on ...

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Clinical Trial: Home-Based Exercise Program for African Americans with MS (TEAAMS)

The goal of the TEAAMS study is to examine whether a home-based exercise training program can provide improvements in walking dysfunction, symptoms, and quality of life among Black and African Americans with MS who live in the Southern US. Participants will exercise at their c...

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Clinical Trial: Impact of Vancomycin on the Gut Microbiome and Immune Function in MS

The goal of this study is to see if changes in the gut microbiome can alter multiple sclerosis outcomes. Participants are newly diagnosed with MS (symptoms onset lest than 6 months) who have never taken disease-modifying treatment. Participants will take vancomycin, an antib...

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Participate in a Clinical Trial

Clinical Trials in MS

NARCOMS Patient Registry

Posting a Trial

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Clinical Trials In Your Area

Clinical Trial: Comparing Experimental Tolebrutinib with Aubagio® in Relapsing MS

Clinical Trial: Computerized Cognitive Rehabilitation

Clinical Trial: Efficacy of Diet on Quality of Life in MS

Clinical Trial: Evaluating Mobility Interventions in the Real World

Clinical Trial: Exercise Training Effects on Cognition and Brain Function in MS

Clinical Trial: Exploratory Study of Entire-body PET Scans for Multiple Sclerosis

Clinical Trial: Fenebrutinib

Clinical Trial: Gait training to improve walking

Clinical Trial: Home-Based Exercise Program for African Americans with MS (TEAAMS)

Clinical Trial: Impact of Vancomycin on the Gut Microbiome and Immune Function in MS

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