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Participate in a Clinical Trial

Without the participation of people with MS, it would be impossible to develop new and better therapies and other interventions.

Clinical Trials in MS


The latest clinical research in MS, including trials funded by the Society and trials in progressive MS.

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Posting a Trial

If you would like us to post a study on these pages, please email studies@nmss.org to find out what information you need to submit for review.

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Clinical trials help to determine if treatments are safe and effective. Studies are monitored to ensure that the rights and safety of all participants are protected. Make an informed decision before agreeing to participate. Read more in our Guide to Participating in Clinical Trials.

Clinical Trials In Your Area

Interested in clinical trials? Simply search by state, type of MS or keyword and see what’s going on in your area.

  1. Clinical Trial: Improving New Learning and Memory in MS

    The Kessler Foundation is currently recruiting for a study on memory. Participants will be compensated.. The study involves paper-and-pencil testing and is intended to assess the efficacy of learning and memory techniques within the Multiple Sclerosis population. Additionally,...
  2. Clinical Trial: IMS001 in people with MS

    The purpose of this research is to determine the safety, tolerability, efficacy, and optimal dose regimen of an investigational human embryonic stem cell derived (hESC) mesenchymal stem cell (MSC) product to treat MS called IMS001.Taking part in this research will last for up ...
  3. Clinical Trial: IMU-838 in Adults with Progressive MS

    This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate efficacy, safety, and tolerability of IMU-838 in people between 18 and 65 years old with primary or secondary progressive multiple sclerosis. Participants will be randomly assigned to receive...
  4. Clinical Trial: IMU-838 versus Placebo in Adults with Relapsing MS

    These are two multi-center, randomized, double-blinded phase 3 studies to evaluate the efficacy, safety, and tolerability of IMU-838 versus placebo in adults (male or female between 18 and 55 years old) with relapsing multiple sclerosis (also called ENSURE-1 and ENSURE-2). Eac...
  5. Clinical Trial: Mood and Exercise Training Study for MS

    METS for MS involves the remote delivery of a 4-month exercise training program with a 4-month follow-up period for persons with multiple sclerosis who have depression. The training programs involve either a combination of walking and resistance training or stretching. The ex...
  6. Clinical Trial: Mood and Exercise Training Study for Multiple Sclerosis

    METS for MS involves the remote delivery of a 4-month exercise training program with a 4-month follow-up period for persons with multiple sclerosis who have depression. The training programs involve either a combination of walking and resistance training or stretching. The exe...
  7. Clinical Trial: Motor Neuroprosthesis to restore motor control in people with severe impairment to both arms and legs

    The Synchron Motor NeuroProsthesis (MNP) is a brain-computer interface intended to improve functional independence and communication of healthcare needs for people who have impaired ability to move their arms and legs. This new device and surgical technique has been developed ...
  8. Clinical trial: MS self-management app

    Many people with MS have been looking for a self-management app tailored to their needs in managing MS and health needs on their MS journey. Researchers at the University of Illinois worked with MS patients and clinicians to develop a new self-management app, SavvyHealth. We n...
  9. Clinical Trial: Multiple Sclerosis Online Course

    Course duration: 24 July to 3 Sep 2023 Estimate effort: 1-2 hr per week Cost fee: Free Content: Introduction to MS, diet, vitamin D, exercise, mindfulness, medication, pregnancy, family & prevention Eligibility: Adults with diagnosed MS The MS Online Course study ...
  10. Clinical Trial: Ocrelizumab for Preventing MS in Individuals With Radiologically Isolated Disease

    “Radiologically isolated syndrome” (RIS) is diagnosed when it is discovered that someone has brain MRI abnormalities similar in appearance and location to abnormalities seen in people with MS. People with RIS are typically otherwise healthy and without any symptoms common for ...
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